Musar sur Avot 2:11

Adam ruined this state of affairs by interfering with the סוד היין, the mystical properties of the grapes. [I suppose that this is based on the tree of knowledge having been a grape bearing tree. Ed.] He followed an evil path by squeezing a cluster of grapes (and consuming its juice). Had he not done so, that "wine" would have remained in the state of what our sages call the יין המשומר בענביו, "the wine that remained preserved within its grapes (compare Berachot 34).” In that event he would have been like "the cistern that does not lose a single drop” [hyperbole for total recall, see Avot 2,11. Ed.]. He would have retained all the holiness that had been his when he was created. When Adam sinned, he did not only lose some of his former glory, fall from a "high roof" (to the ground), but he fell into a "very deep pit" (below the ground). This was a בור רק, an empty pit [allusion to the pit Joseph had been thrown in. Genesis 37,24], since it did not even contain the ingredients for the survival of the species. The species was wiped out at the time of the deluge as a direct consequence of Adam having polluted that "drop of sacred semen," and made it "evil smelling." Due to G–d's personal intervention, Noach was saved seeing he was righteous, and the righteous are the foundation of the universe. The present universe was founded by him as a result.

Pele Yoetz – on Sinah - Hatred - Hatred [of others] is hated [by Hash-m] for upon it the Tanna said Rabbi Yehoshua says a bad eye & the evil inclination & hatred of the creatures [of Hash-m], expel a person from the world. (Pirkei Avot 2:11 on Self-Destruction And it causes many sins for hatred awakens quarrels & one falls into the grips of controversy & evil speech & causes one to become happy for the misfortune [of others] & to damage & cause pain & to take vengeance & to spite like a snake [against the other] & many similar evils. And it is written in the holy books – that there is no sin of all the sins like hatred – because every moment one transgresses upon that that is written in the Torah “Do not hate your brother in your heart.” and that that is written “You shall love your fellow as yourself.” & this is the reason why gratuitous hatred destroyed the Holy Temple. And any kind of of hatred is considered 'gratuitous hatred', for any kind of claims that he has [against the other party] to express, are vanity, acts of delusion, like we explained above in the section of 'love of [our] fellows' - see there.